CollGel™ SERIES BIOINK
3D BIOPRINTING FOR TISSUE ENGINEERING
CUSTOMISABLE STIFFNESS
CollGel-01 allows precise adjustment of collagen concentration to fine-tune mechanical strength, viscosity, and rheological performance. This enables researchers to match the mechanical environment of various native tissues, supporting the fabrication of constructs with defined structural properties. Its tunability in stiffness is critical for building scaffolds suited to different tissue engineering needs, from soft connective tissues to more load-bearing architectures.
TAILORED FORMULATION VERSATILITY
Designed for flexible reconstitution, CollGel-01 can be mixed with PBS, culture media, or water to suit specific experimental conditions. Its ECM-inspired composition allows integration with materials such as gelatin, hyaluronic acid, and methacrylated polymers.This versatility supports the development of hybrid bioinks for advanced scaffold design, enhancing both mechanical properties and biofunctionality across diverse tissue applications.
"CollGel-01 offers precise control over ECM concentration and fiber organization, enabling the fabrication of tissue constructs that closely mimic the biomechanical properties of native organs. By adjusting collagen stiffness and matrix density, researchers can match the physical environments of soft tissues such as brain or lung at lower concentrations, and replicate stiffer tissues like cartilage, tendon, or bone at higher concentrations.
This biomimetic flexibility supports tissue-specific scaffold design and enhances cell–matrix interactions, providing a platform for guiding cellular behaviour, promoting functional tissue development, and advancing next-generation regenerative strategies."
Bioink: 6% COLLGEL-01 [1X PBS]
Without Cell-Laden
Extrusion Printing [Directly]
ADAPTBILITY TO 3D BIOPRITNING
CollGel-01 supports high-resolution bioprinting with excellent structural fidelity. At physiological ionic strength, it undergoes controlled fibrillogenesis, forming stable hydrogels that retain printed geometry.
• At >5% collagen concentration, it supports direct writing in air, eliminating the need for support gels, making it ideal for freeform bioprinting.
• At <3% collagen concentration, it allows for direct injection or seamless integration with GelMA, expanding its versatility for SLA and inkjet bioprinting in tissue engineering and biomaterial hybridisation.
BIOCOMPATIBILITY AND ECM MIMICRY
Produced from medical-grade type I atelocollagen, CollGel-01 offers high purity and minimal immunogenicity. Its pH-neutral, purified formulation self-assembles into a fibrillar matrix that closely resembles native extracellular matrix, supporting cell adhesion, migration, and tissue-specific organisation.
Optimised for cell encapsulation, it enables uniform cell distribution and high viability, making it a reliable platform for biologically relevant tissue model construction.
Bioink: 6% COLLGEL-01 [1X PBS]
Cell-Laden [Human Fibroblast]
Day 7 L/D
Extrusion Printing [Directly]
CollGel™ SERIES BIOINK
IN VITRO MODEL FOR DRUG DISCOVERY
TUNABLE BIOINK PROPERTIES
CollGel-01 offers adjustable stiffness and viscosity, making it suitable for a wide range of in vitro systems, from 2D coatings to 3D bioprinted constructs and organoid models.
By modulating collagen concentration, researchers can mimic the mechanical cues of native tissues, allowing fine-tuned control over cell behaviour in experimental setups. This adaptability supports the development of biologically relevant models for drug screening, stem cell studies, and disease modelling.
Bioink: 3% COLLGEL-01 [1X PBS]
With Cell-Laden [Human Epithelial Cells]
Day 28
Extrusion Printing [Directly]
NATURAL GELATION AND THERMAL STABILITY
Under physiological conditions, CollGel-01 undergoes self-assembly into a fibrillar hydrogel without requiring chemical crosslinkers.
Forming at neutral pH and body temperature (37°C), the matrix offers thermal stability and long-term mechanical support. This allows cells to grow within a stable, ECM-like microenvironment over extended culture periods, preserving hydrogel integrity and cellular function throughout experimental timelines.
BATCH CONSISTENCY
Manufactured under GMP-compliant conditions and filled using the Inktegration™ system, CollGel-01 ensures reliable batch-to-batch reproducibility. Its endotoxin-free, sealed format safeguards sterility and structural uniformity, supporting high-throughput workflows without compromising material quality.
These properties are critical for consistent data generation in toxicity studies, drug response profiling, and regenerative assay development.
CollGel™ SERIES BIOINK
REGENERATIVE MEDICINE AND CELL THERAPY
For Research Use Only
CollGel™ Series bioinks are intended exclusively for research laboratories. While manufactured using medical-grade processes and high-purity materials, these products are not approved for human or clinical use.
Regulatory authorisation is required for any future medical applications, which are currently under exploration.
CLINICAL VERSATILITY
CollGel™ is engineered as a flexible bioink platform for injectable cell delivery and bioprinted tissue constructs, currently designated for research use only (RUO).
With excellent cell encapsulation capacity and injectability, it creates a protective and biomimetic matrix that maintains high stem cell viability and retention at the target site. Its tunable formulation allows for the incorporation of therapeutic molecules such as growth factors or cytokines, offering a modular approach for developing regenerative treatments and personalised biofabrication strategies.
Room Temp. Restoration
Individual Vacuum Packed
STORAGE STABILITY
Supplied in a lyophilised format, CollGel™ bioinks eliminate the need for refrigeration, supporting long-term storage and easy transport.
This shelf-stable design reduces logistical constraints, making the material suitable for use in remote clinical settings and resource-limited environments. Its compact and durable format also lends itself to emerging scenarios in space healthcare, where materials must remain functional across extended missions and under extreme environmental conditions.
FROM BENCH TO BEDSIDE
Manufactured from ISO 13485-certified medical-grade raw materials and processed in GMP-compliant facilities, CollGel™ is formulated to support the path from preclinical research to potential clinical application.While currently RUO-designated, its consistent performance, scalability, and regulatory-ready standards make it ideal for proof-of-concept studies, translational collaborations, and long-term innovation pipelines.
We are actively advancing the clinical readiness of CollGel™, aiming to empower both researchers and clinicians in the development of next-generation regenerative therapies.
INKTEGRATION™ - SIMPLE IS POSSIBLE
[01]
FORMULATION DESIGN
COLLAGEN CONCENTRATION
[1X PBS/MEDIUM/H2O]
[02]
RECONSTITUTION
BACK AND FORTH [FULLY RECONSTITUTED]
WATCH UP YOUR THUMBS
[03]
COLLAGEN FIBRILLOGENESIS
KEEP 4°C ~12 HOURS - OVERNIGHT
[04]
READY TO PRINT
OR MIX WITH CELLS BEFORE PRINTING